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DeCS
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Descritor Inglês:
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Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Descritor Espanhol:
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Dioxigenasa FTO Dependiente de Alfa-Cetoglutarato
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Descritor Português:
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Dioxigenase FTO Dependente de alfa-Cetoglutarato
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Sinônimos Inglês:
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AlkB Homolog 9 Protein
Alpha-Ketoglutarate-Dependent Dioxygenase
Fat Mass and Obesity Associated (FTO) Protein
Fat Mass and Obesity Associated Protein
Alpha Ketoglutarate Dependent Dioxygenase
Alpha Ketoglutarate Dependent Dioxygenase FTO
Dioxygenase, Alpha-Ketoglutarate-Dependent
FTO, Alpha-Ketoglutarate-Dependent Dioxygenase
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Categoria:
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D08.811.074.062.968
D08.811.682.662.582.242
D08.811.682.690.416.139.992
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Definição Inglês:
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A dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. It has highest activity towards single-stranded RNA containing 3-methyluracil, followed by SINGLE-STRANDED DNA containing 3-methylthymine and specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA (mRNA) in higher EUKARYOTES. It contributes to the regulation of the global metabolic rate, energy HOMEOSTASIS, as well as body fat accumulation by regulating the differentiation of ADIPOCYTES into BROWN FAT CELLS or WHITE FAT CELLS. |
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Nota Histórica Inglês:
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2017
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Qualificadores Permitidos Inglês:
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Número do Registro:
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56463
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Identificador Único:
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D000071516
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Ocorrência na BVS:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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